Anti-Human GZMA Monoclonal Antibody (1A612) from ProteoGenix; catalogue ARO-A23377; research use only.
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The Anti-Human GZMA Monoclonal Antibody (1A612) is a cutting-edge biotech product designed to enhance the function of immune cells in the human body. This powerful antibody targets the GZMA protein, a key player in the immune response against foreign invaders. With its high specificity and efficiency, this antibody has become a valuable tool for researchers and clinicians in the field of immunology.
The Anti-Human GZMA Monoclonal Antibody (1A612) works by binding to the GZMA protein, which is found in cytotoxic T cells and natural killer cells. This binding activates these immune cells, triggering them to release cytotoxic granules that can destroy infected or cancerous cells. This process, known as apoptosis, is crucial for the body’s defense against pathogens and abnormal cells.
The main application of Anti-Human GZMA Monoclonal Antibody (1A612) is in immunotherapy, particularly in the treatment of cancer. By targeting GZMA, this antibody can enhance the cytotoxic activity of immune cells, making them more effective in killing cancer cells. It has also shown promising results in autoimmune diseases, where the immune system mistakenly attacks healthy cells.
The Anti-Human GZMA Monoclonal Antibody (1A612) has been extensively studied in various experimental models, demonstrating its potential in different areas of research. In one study, it was found to significantly inhibit tumor growth in a mouse model of melanoma. In another study, it showed promising results in treating rheumatoid arthritis in a mouse model. These findings highlight the versatility and potential of this antibody in various research fields.
This antibody has been extensively researched and proven to be effective in targeting GZMA, enhancing immune cell function, and treating various diseases. With its high specificity and efficiency, it is a valuable tool in immunotherapy and autoimmune disease research. Its potential has been demonstrated in multiple experimental models, making it a promising candidate for further studies.
In conclusion, the Anti-Human GZMA Monoclonal Antibody (1A612) is a powerful biotech product that can unlock the full potential of immune cells. Its ability to target GZMA and enhance immune cell function makes it a valuable tool in cancer treatment and autoimmune disease research. With its proven effectiveness and versatility, this antibody is a must-have for any researcher or clinician in the field of immunology.
ProteoGenix catalogue number ARO-A23377. For research use only.
Target: Granzyme A, EC:3.4.21.78, CTL tryptase, Cytotoxic T-lymphocyte proteinase 1, Fragmentin-1, Granzyme-1, Hanukkah factor, H factor, HF, GZMA; Clonality: Monoclonal Antibody; Reactivity: Human; Applications: ELISA, IHC.
Available configurations: 50ug, 100ug, 1mg.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP | ELISA | IHC |
|---|---|---|---|---|---|---|---|---|---|
| Human |
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
