Manufactured by:Promab
RUO

Anti-RYK Mouse Monoclonal Antibody

RYK antibody from Promab.

SKU:
ABM416754-1
Product type
Primary antibodies
TargetRYK
ApplicationsWB, Flow Cytometry
Species / reactivityHuman, Mouse

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

RYK may be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. RYK is involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.

For research use only.

Key facts & specifications
Also known as
Tyrosine-protein kinase RYK; 2.7.10.1; RYK; JTK5A; receptor like tyrosine kinase; Inactive tyrosine-protein kinase RYK
Host species
Mouse
Clonality
Monoclonal
Conjugation
Unconjugated
Immunogen
This RYK antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 260-565 amino acids from human RYK.
Molecular weight
67.8 kDa
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Mouse
Identifiers & database references
Gene symbol
RYK
Gene ID
6259
UniProt accession
P34925
Ensembl
ENSG00000163785
HGNC
10481
OMIM
600524
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Promab
£174.20