Mouse MFGE8 / Lactadherin / Milk Fat Globule 1 ELISA Kit PicoKine®

Mouse MFGE8 / Lactadherin / Milk Fat Globule 1 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Mfge8 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

MFGE8 (Milk Fat Globule-Egf Factor 8), also called as Lactadherin or SED1, is a protein which in humans is encoded by the MFGE8 gene. Mfge8 is secreted protein found in vertebrates, including mammals as well as birds. By fluorescence in situ hybridization, the MFGE8 gene was mapped to chromosome 15q25. MFGE8 is a factor that links apoptotic cells to phagocytes. It specifically bound to apoptotic cells by recognizing aminophospholipids such as phosphatidylserine. MFGE8, when engaged by phospholipids, bound to cells via its RGD motif. It bound particularly strongly to cells expressing alpha-V-beta-3 integrin. It showed that Mfge8 was expressed in intestinal lamina propria macrophages in mice. Using a wound-healing assay, they showed that Mfge8 promoted migration of intestinal epithelial cells through a PKC-epsilon (PRKCE)-dependent mechanism.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK1194
Product category	PicoKine® ELISA Kits
Reactive species	Mouse
Tested applications	ELISA
Gene name	MFGE8
Protein name	Lactadherin
Sample type	cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).
Assay range	62.5 pg/ml - 4,000 pg/ml
Sensitivity	<10 pg/ml
Specificity	Natural and recombinant mouse MFGE8
Immunogen	Expression system for standard: NS0; Immunogen sequence: A23-C463
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P21956
NCBI Gene ID	17304

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.