Mouse FCRN/FCGRT ELISA Kit PicoKine®

Mouse FCRN/FCGRT ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Fcgrt in cell culture supernatants, serum, plasma (heparin, EDTA) and cell lysates. Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

The neonatal Fc receptor (FcRn), also known as the Brambell receptor, is a protein that in humans is encoded by the FCGRT gene. The neonatal Fc receptor is an Fc receptor which is similar in structure to the MHC class I molecule and also associates with beta-2-microglobulin. It was first discovered in rodents as a unique receptor capable of transporting IgG from mother's milk across the epithelium of newborn rodent's gut into the newborn's bloodstream. Further studies revealed a similar receptor in humans, leading to the naming as a neonatal Fc receptor. In humans, however, it is found in the placenta to help facilitate transport of mother's IgG to the growing fetus and it has also been shown to play a role in monitoring IgG turnover. Neonatal Fc receptor expression is up-regulated by the proinflammatory cytokine,TNF-α, and down-regulated by IFN-γ.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK1454
Product category	PicoKine® ELISA Kits
Reactive species	Mouse
Tested applications	ELISA
Gene name	Fcgrt
Protein name	IgG receptor FcRn large subunit p51
Sample type	cell culture supernatants, serum, plasma (heparin, EDTA) and cell lysates.
Assay range	93.7 pg/ml - 6,000 pg/ml
Sensitivity	<10 pg/ml
Specificity	Natural and recombinant mouse FCRN
Immunogen	Expression system for standard: NS0; Immunogen sequence: S22-S297
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	Q61559
NCBI Gene ID	14132

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.