ELISA Kit supplied by Boster Bio
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Human Total Bcl-2 ELISA Kit PicoKine® is a research-use ELISA kit from Boster Bio for measuring BCL2 in Cell lysates samples from Human. Use the listed assay range, sample guidance and protocol documents to assess suitability for the intended study.
Human Total Bcl-2 ELISA Kit PicoKine® (96 Tests). Quantitate Human Total Bcl-2 in cell lysates. Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.Bcl-2-like protein 1, also known as Bcl-X, is a protein that in humans is encoded by the BCL2L1 gene. The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform (Bcl-xL) acts as an apoptotic inhibitor and the shorter form (Bcl-xS) acts as an apoptotic activator.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Sample Compatibility | Assay Range | Sensitivity | Specificity |
|---|---|---|---|---|
| cell lysates |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
BCL2 apoptosis regulator (BCL2; Bcl-2) is an anti-apoptotic mitochondrial membrane protein. This target guide connects human NCBI Gene 596, UniProtKB P10415 and ABMIUM catalogue products associated with BCL2.
Biological function: BCL2 apoptosis regulator, commonly called Bcl-2, suppresses programmed cell death in multiple cell systems and regulates apoptosis through effects on mitochondrial membrane permeability and cytochrome-c release. Its cell-survival role makes BCL2 a central target in apoptosis, mitochondrial signalling, lymphocyte biology and cancer research.
