Human TIE2/TEK ELISA Kit PicoKine®

Human TIE2 ELISA Kit PicoKine® (96 Tests). Quantitate Human TEK in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 5pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Tyrosine kinase with Ig and EGF homology domain 2 (Tie-2), also called TEK tyrosine kinase, endothelial (TEK). Tie-2 and tie-1 are expressed in early embryonic vascular system and in maternal decidual vascular endothelial cells, where the vasculature undergoes an active angiogenesis. Tie-2, but not tie-1, expression was also detected in extraembryonic mesoderm of the amnion. Angiogenesis is coordinated with follicular cell growth in goitrogenesis. The angiopoietins, Ang-1 and Ang-2, are angiogenic growth factors acting through Tie-2. Tie-2 and Ang-1 are expressed in thyroid epithelial and endothelial cells, and Tie-2 is regulated by TSH and cAMP in follicular cells. And Tie-2 expression is increased in goiter in both humans and rats, consistent with a role in goitrogenesis. Tie2/Ang-1 signaling pathway plays a critical role in the maintenance of HSCs in a quiescent state in the BM niche. And the Tie-2 signaling pathway is also critical for endothelial cell-smooth muscle cell communication in venous morphogenesis.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK0519
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	TEK
Protein name	Angiopoietin-1 receptor
Sample type	cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).
Assay range	156 pg/ml - 10,000 pg/ml
Sensitivity	<5 pg/ml
Specificity	Natural and recombinant human TIE2
Immunogen	Expression system for standard: NS0; Immunogen sequence: A23-K745
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	Q02763
NCBI Gene ID	7010

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.