Human RET ELISA Kit PicoKine®

Human RET ELISA Kit PicoKine® (96 Tests). Quantitate Human RET in cell culture supernatants, serum and plasma (heparin). Sensitivity: 15pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. It is mapped to 10q11.21. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related proteins to the encoded receptor stimulates receptor dimerization and activation of downstream signaling pathways that play a role in cell differentiation, growth, migration and survival. The encoded receptor is important in development of the nervous system, and the development of organs and tissues derived from the neural crest. This proto-oncogene can undergo oncogenic activation through both cytogenetic rearrangement and activating point mutations. Mutations in this gene are associated with Hirschsprung disease and central hypoventilation syndrome and have been identified in patients with renal agenesis.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK1877
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	RET
Protein name	Proto-oncogene tyrosine-protein kinase receptor Ret
Sample type	cell culture supernatants, serum and plasma (heparin).
Assay range	93.8 pg/ml - 6,000 pg/ml
Sensitivity	<15 pg/ml
Specificity	Natural and recombinant human RET
Immunogen	Expression system for standard: NS0; Immunogen sequence: L29-R635
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P07949
NCBI Gene ID	5979

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.