Human Properdin / Complement Factor P ELISA Kit PicoKine®

Human Properdin / Complement Factor P ELISA Kit PicoKine® (96 Tests). Quantitate Human CFP in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Properdin or Factor P is the only known positive regulator of complement activation that stabilizes thealternative pathway convertases. This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK1653
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	CFP
Protein name	Properdin
Sample type	cell culture supernatants, serum and plasma (heparin, EDTA).
Assay range	312 pg/ml - 20,000 pg/ml
Sensitivity	<10 pg/ml
Specificity	Natural and recombinant human Properdin
Immunogen	Expression system for standard: NS0; Immunogen sequence: D28-L469
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P27918
NCBI Gene ID	5199

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.