Human/Mouse COX-2 ELISA Kit PicoKine®
ELISA Kit supplied by Boster Bio Read more ›

Product Description
Cyclooxygenase-2 (COX-2), also known as Prostaglandin-endoperoxide synthase 2 (HUGO PTGS2), is an enzyme that in humans is encoded by the PTGS2 gene. PTGS2 (prostaglandin-endoperoxide synthase 2) is a gene that encodes an enzyme responsible for catalyzing the conversion of arachidonic acid into prostaglandins. Prostaglandins are lipid signaling molecules that play crucial roles in regulating inflammation, pain, and reproductive processes. PTGS2 is expressed in various tissues, particularly in sites of inflammation and certain tumor cells, where its expression levels are often significantly elevated. The activity of this gene is regulated by various stimuli, including cytokines, hormones, and growth factors, making it a key player in pathological conditions such as inflammation, cancer, and cardiovascular diseases. Due to its involvement in these diseases, PTGS2 has become a potential drug target, especially in the development of nonsteroidal anti-inflammatory drugs (NSAIDs).
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | EK2289 |
| Product category | PicoKine® ELISA Kits |
| Reactive species | Human, Mouse |
| Tested applications | ELISA |
| Gene name | PTGS2 |
| Protein name | Prostaglandin G/H synthase 2 |
| Sample type | cell lysates. |
| Assay range | 156 pg/ml - 10,000 pg/ml |
| Sensitivity | <20 pg/ml |
| Immunogen | Expression system for standard: NS0; Immunogen sequence: A18-L604 |
| Storage | Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | P35354 |
| NCBI Gene ID | 5743 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | Prostaglandin G/H synthase 2 |
| Also known as | COX 2; COX2; COX2/ Cyclooxygenase 2; COX2/ Cyclooxygenase 2/ PTGS2; Cyclooxygenase 2; GRIPGHS; hCox 2; PGG/HS; PGH synthase 2; PGHS 2; PHS 2; PHS II; Prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; PTGS2 |
| Species reactivity | Human,Mouse |
| Shelf life | Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Sensitivity | <20 pg/ml |
| Detection range | 156 pg/ml - 10,000 pg/ml |
| Sample types |
cell lysates.
See sample validation ›
|
Sample Type Validation
1 sample type| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell lysates. |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.