Human IL4R ELISA Kit PicoKine®

Human IL4R ELISA Kit PicoKine® (96 Tests). Quantitate Human IL4R in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

The interleukin 4 receptor is a type I cytokine receptor. IL4R is its human gene. It is mapped to 16p12.1. This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK2092
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	IL4R
Protein name	Interleukin-4 receptor subunit alpha
Sample type	cell culture supernatants, serum and plasma (heparin, EDTA, citrate).
Assay range	46.9 pg/ml - 3,000 pg/ml
Sensitivity	<10 pg/ml
Specificity	Natural and recombinant human IL4R
Immunogen	Expression system for standard: NS0; Immunogen sequence: M26-H232
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P24394
NCBI Gene ID	3566

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.