Human HEXA ELISA Kit PicoKine®

Human HEXA Kit PicoKine® (96 Tests). Quantitate Human HEXA in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 50 pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Hexosaminidase A (alpha polypeptide), also known as HEXA, is an enzyme that in humans is encoded by the HEXA gene, located on the 15th chromosome. This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK2215
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	HEXA
Protein name	Beta-hexosaminidase subunit alpha
Sample type	cell culture supernatants, serum and plasma (heparin, EDTA)
Assay range	312 pg/ml - 20,000 pg/ml
Sensitivity	<50 pg/ml
Specificity	Natural and recombinant human HEXA
Immunogen	Expression system for standard: NS0; Immunogen sequence: M1-T529
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P06865
NCBI Gene ID	3073

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.