Human Granulysin ELISA Kit PicoKine®

Human Granulysin ELISA Kit PicoKine® (96 Tests). Quantitate Human GNLY in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Granulysin is a substance released by cytotoxic T cells (CD8) when they are attached to infected body cells. The product of this gene is a member of the saposin-like protein (SAPLIP) family. It is mapped to 2p11.2. Granulysin functions to create holes in the target cell membrane and destroy it. It is able to induce apoptosis in target cells and also has antimicrobial action. This gene is expressed in cytolytic granules with perforin, a pore forming protein, and granzymes that are also involved in cytolysis. In addition to it, Granulysin is broadly antimicrobial, killing microbes that cause, for example, tuberculosis and malaria, and can destroy some tumors. A series of peptides generated from the amino acid sequence of Granulysin are potential antibiotics. It has been found that secretory Granulysin is a key molecule responsible for the disseminated keratinocyte death in SJS/TEN.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK1280
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	GNLY
Protein name	Granulysin
Sample type	cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).
Assay range	31.2 pg/ml - 2,000 pg/ml
Sensitivity	<10 pg/ml
Specificity	Natural and recombinant human Granulysin
Immunogen	Expression system for standard: NS0; Immunogen sequence: M1-L145
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P22749
NCBI Gene ID	10578

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.