Human Complement C2 ELISA Kit PicoKine®

Human Complement C2 ELISA Kit PicoKine® (96 Tests). Quantitate Human C2 in cell culture supernatants, serum, plasma(heparin, EDTA, citrate) and urine. Sensitivity: 20 pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Complement C2 is a protein that in humans is encoded by the C2 gene. Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK2143
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	C2
Protein name	Complement C2
Sample type	cell culture supernatants, serum, plasma(heparin, EDTA, citrate) and urine
Assay range	312 pg/ml - 20,000 pg/ml
Sensitivity	<20 pg/ml
Specificity	Natural and recombinant human C2
Immunogen	Expression system for standard: NS0; Immunogen sequence: A21-L752
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P06681
NCBI Gene ID	717

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.