TMPRSS2/ETV4 Fusion FISH Probe Reagent

FP-010-3 TMPRSS2/21Q22/ETV4/17Q21 Fusion FISH probe reagent TMPRSS2 oragen, ETV4 green

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Manufactured by:Wuhan HealthCare Biotechnology
Save 15%RUO

TMPRSS2/ETV4 Fusion FISH Probe Reagent

Research-use TMPRSS2/ETV4 fusion FISH probe for studying rearrangements involving TMPRSS2/ETV4 at 21q22, 17q21 by fluorescence in situ hybridisation.

SKU:
ABM46294
Manufacturer SKU
FP-010-3
Product type
FISH Probe Reagent
TargetTMPRSS2/21Q22/ETV4/17Q21
ApplicationsFISH
Sample typeTissue

Manufacturer provenance

Manufactured by:
Wuhan HealthCare Biotechnology
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Research-use TMPRSS2/ETV4 fusion FISH probe for studying rearrangements involving TMPRSS2/ETV4 at 21q22, 17q21 by fluorescence in situ hybridisation.

The manufacturer assigns TMPRSS2 at 21q22 to the orange channel and ETV4 at 17q21 to the green channel. The associated manufacturer probe map shows the TMPRSS2 region divided across labelled segments around the gene and an ETV4 region spanning approximately 910 kb.

Probe design

  • Targets: TMPRSS2 and ETV4
  • TMPRSS2 locus: 21q22, orange
  • ETV4 locus: 17q21, green
  • ETV4 mapped region: approximately 910 kb
  • Probe format: fusion / gene-anomaly research
  • Pack size: 100 µL/kit, 10 tests
  • Regulatory status: Research Use Only (RUO)
Wuhan HealthCare Biotechnology TMPRSS2 ETV4 probe design map
Manufacturer probe-design map for. Source: Wuhan HealthCare Biotechnology.

Research context

Wuhan HealthCare Biotechnology lists this probe under urological-tumour applications and describes TMPRSS2/ETV4 rearrangements in prostate-cancer research. ABMIUM presents that association as research context only. The reagent is supplied for research use and not for clinical diagnosis.

Key facts & specifications
Research areas
Cytogenetics, Oncology research, Haematology research, Solid Tumors research
Also known as
ERG, TMPRSS2, ETV1, ETV4 gene anomaly detection probe (TMPRSS2/ETV4), TMPRSS2(21q22)/ETV4(17q21)
Available conjugations
TMPRSS2 oragen, ETV4 green, orange, green, aqua, DAPI
Incubation temperature
42 °C
Assay type
Fluorescence in situ hybridisation (FISH)
Detection method
Fluorescence microscopy
Wells / tests
10 tests
Form / buffer
Ready-to-use FISH probe reagent
Sequence fragment
TMPRSS2(21q22)/ETV4(17q21)
Quantity per pack
100µL/kit / 10 tests
Technical note
Probe design source text: TMPRSS2 gene (21q22) labeled as orange; , ETV4 gene (17q21) labeled as green. Protocol / imaging data: Hybridisation temperature: 42 °C; Hybridisation time: 2-16h; Denaturation temperature: 85°C; Denaturation time: 5min; Recommended imaging filters: DAPI + orange +green; Counterstain: DAPI; Signal interpretation: Refer to IFU; Expected normal signal pattern: Refer to IFU Label assignment: TMPRSS2 oragen, ETV4 green Cytoband(s): 21q22, 17q21
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Sample type validation

Sample compatibility evidence using the same validation key.

Sample typeCompatible
Tissue
Identifiers & database references
Manufacturer SKU
FP-010-3
Storage, stability & shipping
Shelf life
20 months
Storage conditions
-20 °C ± 5 °C
Shipped at
below 0 °C
Short-term storage
below 0 °C
Long-term storage
-20 °C ± 5 °C
Storage warning
Protect fluorescent probe reagent from light during handling.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Wuhan HealthCare Biotechnology and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Wuhan HealthCare Biotechnology
£675.00£574.00