CCND1 (BCL1) Break-Apart FISH Probe Reagent

FP-042 CCND1/11Q13.3 Break-apart FISH probe reagent CCND1 3' orange, CCND1 5' green

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Manufactured by:Wuhan HealthCare Biotechnology
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CCND1 (BCL1) Break-Apart FISH Probe Reagent

Research-use CCND1 (BCL1) break-apart FISH probe for studying genomic rearrangements involving CCND1 (BCL1) at 11q13.3 by fluorescence in situ hybridisation.

SKU:
ABM46308
Manufacturer SKU
FP-042
Product type
FISH Probe Reagent
TargetCCND1/11Q13.3
ApplicationsFISH
Sample typeCell+Tissue

Manufacturer provenance

Manufactured by:
Wuhan HealthCare Biotechnology
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Research-use CCND1 (BCL1) break-apart FISH probe for studying genomic rearrangements involving CCND1 (BCL1) at 11q13.3 by fluorescence in situ hybridisation.

The manufacturer describes a dual-colour break-apart design with the CCND1 5′ region labelled green over 610 kb and the CCND1 3′ region labelled orange over 580 kb. The manufacturer map shows the two labelled regions separated around the 11q13.3 locus.

Probe design

  • Target: CCND1 (BCL1)
  • Locus: 11q13.3
  • Probe format: Break-apart
  • CCND1 5′ region: green, 610 kb
  • CCND1 3′ region: orange, 580 kb
  • Pack size: 100 µL/kit, 10 tests
  • Regulatory status: Research Use Only (RUO)
Wuhan HealthCare Biotechnology CCND1 break-apart probe design map
Manufacturer probe-design map for. Source: Wuhan HealthCare Biotechnology.

Research context

Wuhan HealthCare Biotechnology lists in lymphoma research and describes it for investigating CCND1 rearrangements. ABMIUM has retained the research association but has not reproduced a translocation designation from the manufacturer overview where the chromosome notation appears internally inconsistent.

Key facts & specifications
Research areas
Cytogenetics, Oncology research, Haematology research, Solid Tumors & Hematological Tumors research
Also known as
CCND1 (BCL1) gene break apart probe reagent, CCND1(11q13.3)
Available conjugations
CCND1 3' orange, CCND1 5' green, orange, green, aqua, DAPI
Incubation temperature
42 °C/45 °C
Assay type
Fluorescence in situ hybridisation (FISH)
Detection method
Fluorescence microscopy
Wells / tests
10 tests
Form / buffer
Ready-to-use FISH probe reagent
Sequence fragment
CCND1(11q13.3)
Quantity per pack
100µL/kit / 10 tests
Technical note
Probe design source text: CCND1 (BCL1) gene 5' end labeled as green, with a length of 610 kb; CCND1 (BCL1) gene 3' end labeled as orange, with a length of 580 kb. Protocol / imaging data: Hybridisation temperature: 42 °C/45 °C; Hybridisation time: 2-16h; Denaturation temperature: 88°C/85°C; Denaturation time: 2min/5min; Recommended imaging filters: DAPI + orange +green; Counterstain: DAPI; Signal interpretation: Refer to IFU; Expected normal signal pattern: Refer to IFU Label assignment: CCND1 3' orange, CCND1 5' green Cytoband(s): 11q13.3
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Sample type validation

Sample compatibility evidence using the same validation key.

Sample typeCompatible
Cell+Tissue
Identifiers & database references
Manufacturer SKU
FP-042
Storage, stability & shipping
Shelf life
18 months
Storage conditions
-20 °C ± 5 °C
Shipped at
below 0 °C
Short-term storage
below 0 °C
Long-term storage
-20 °C ± 5 °C
Storage warning
Protect fluorescent probe reagent from light during handling.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Wuhan HealthCare Biotechnology and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Wuhan HealthCare Biotechnology
£675.00£574.00