PAR6G rabbit pAb from ELK Biotechnology Read more ›
PAR6G rabbit pAb is a research-use antibody from ELK Biotechnology for studying PAR6G in WB, ELISA workflows with listed reactivity for Human, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.
domain:The pseudo-CRIB domain together with the PDZ domain is required for the interaction with Rho small GTPases.,function:Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.,similarity:Belongs to the PAR6 family.,similarity:Contains 1 OPR domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 pseudo-CRIB domain.,subunit:Interacts with PARD3 (Probable). Interacts with GTP-bound forms of CDC42, ARHQ/TC10 and RAC1. Interacts with the N-terminal part of PRKCI and PRKCZ.,tissue specificity:Widely expressed, with a higher expression in fetal and adult kidney.,
| Specificity | PAR6G Polyclonal Antibody detects endogenous levels of protein. |
|---|---|
| Validation evidence captions | Western blot analysis of lysates from HCT116 cells, primary antibody was diluted at 1:1000, 4°over night |
| Collaborator | ELK Biotechnology |
| Partner model | ES9974 |
| Target | PAR6G |
| Research areas | >>Rap1 signaling pathway, >>Endocytosis, >>Axon guidance, >>Hippo signaling pathway, >>Tight junction, >>Human papillomavirus infection |
| Reactivity | Human,Mouse |
| Applications | WB,ELISA |
| Conjugation | Unconjugated |
| Dilution range | WB 1:500-2000 ELISA 1:5000-20000 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 240-320 |
| Concentration | 1 mg/ml |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Assay type | Antibody validation/application |
| Expression system | Widely expressed, with a higher expression in fetal and adult kidney. |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Mouse |
| Species | Dilution | Notes |
|---|---|---|
| Human | WB 1:500-2000 ELISA 1:5000-20000 | — |
| Mouse | — | — |
| Species | Dilution | Notes |
|---|
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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