Collaborator ELK Biotechnology
Primary AntibodyISO 9001:2015
ABM100292

CANB1 rabbit pAb

ISO 9001|ABMIUM Verified™|Antibody

CANB1 rabbit pAb from ELK Biotechnology Read more ›

CANB1 rabbit pAb
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CANB1 rabbit pAb

Product Description

CANB1 rabbit pAb is a research-use antibody from ELK Biotechnology for studying CANB1 in WB, ELISA workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.

Background

function:Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.,miscellaneous:This protein has four functional calcium-binding sites.,similarity:Belongs to the calcineurin regulatory subunit family.,similarity:Contains 4 EF-hand domains.,subunit:Composed of a catalytic subunit (A) and a regulatory subunit (B).,

Additional antibody information

Specificity CANB1 Polyclonal Antibody detects endogenous levels of protein.
Validation evidence captions Western blot analysis of lysates from SW480 cells, primary antibody was diluted at 1:1000, 4°over night

Key Facts

Product typePrimary Antibody Target: CANB1
Collaborator ELK Biotechnology
Partner model ES9460
Target CANB1
Research areas>>MAPK signaling pathway, >>Calcium signaling pathway, >>cGMP-PKG signaling pathway, >>Oocyte meiosis, >>Cellular senescence, >>Wnt signaling pathway, >>Axon guidance, >>VEGF signaling pathway, >>Osteoclast differentiation, >>C-type lectin receptor signaling pathway, >>Natural killer cell mediated cytotoxicity, >>Th1 and Th2 cell differentiation, >>Th17 cell differentiation, >>T cell receptor signaling pathway, >>B cell receptor signaling pathway, >>Long-term potentiation, >>Glutamatergic synapse, >>Oxytocin signaling pathway, >>Glucagon signaling pathway, >>Renin secretion, >>Alzheimer disease, >>Amyotrophic lateral sclerosis, >>Prion disease, >>Pathways of neurodegeneration - multiple diseases, >>Amphetamine addiction, >>Tuberculosis, >>Human cytomegalovirus infection, >>Human T-cell leukemia virus 1 infection, >>Kaposi sarcoma-associated herpesvirus infection, >>Human immunodeficiency virus 1 infection, >>PD-L1 expression and PD-1 checkpoint pathway in cancer, >>Lipid and atherosclerosis
Reactivity Human,Mouse,Rat
Applications WB,ELISA
ConjugationUnconjugated
Dilution rangeWB 1:500-2000 ELISA 1:5000-20000
Host Rabbit
Clonality Polyclonal
Isotype IgG
Immunogen Synthesized peptide derived from part region of human protein
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay type Antibody validation/application
Expression system Blood,Fetal brain cortex,
Purity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Application Validation Matrix

3 speciess
ABMIUM Validated™ ABMIUM Verified™ Expected Performance Not suitable
SpeciesWBIHCIFELISAIPFCMChIP
Human
Mouse
Rat
ABMIUM Validated™ WB
Species Dilution Notes
Human WB 1:500-2000 ELISA 1:5000-20000
Mouse
Rat
ABMIUM Validated™ ELISA
Species Dilution Notes

Specifications

Target
CANB1
Concentration
1 mg/ml
Working concentration
WB 1:500-2000 ELISA 1:5000-20000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form / buffer
Liquid
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Species reactivity
Human,Mouse,Rat
Tested applications
WBELISA
Immunogen
Synthesized peptide derived from part region of human protein
Observed band
18kD
Cellular localization
Cytoplasm, cytosol . Cell membrane . Cell membrane, sarcolemma . Cell membrane ; Lipid-anchor . Translocates from the cytosol to the sarcolemma in a CIB1-dependent manner during cardiomyocyte hypertrophy. .
Dilution range
WB 1:500-2000 ELISA 1:5000-20000
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage & Stability

Long-term storage
'-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Compliance & Certifications

ABMIUM
ABMIUM Verified

Collaborator meets ABMIUM quality standards and overall product performance standards have been met.

ISO
ISO 9001

Quality management certification.

RUO
Research Use Only

For research applications. Not for diagnostic use.

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