Paxillin rabbit pAb from ELK Biotechnology Read more ›
Paxillin rabbit pAb is a research-use antibody from ELK Biotechnology for studying Paxillin in WB, ELISA workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.
This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445). [provided by RefSeq, Aug 2011],
| Specificity | Paxillin Polyclonal Antibody detects endogenous levels of Paxillin protein. |
|---|---|
| Validation evidence captions | Western Blot analysis of 293 cells using Paxillin Polyclonal Antibody | Western blot analysis of Paxillin Antibody. The lane on the right is blocked with the Paxillin peptide. | Western blot analysis of the lysates from RAW264.7cells using Paxillin antibody. |
| Collaborator | ELK Biotechnology |
| Partner model | ES6955 |
| Target | Paxillin |
| Research areas | >>Chemokine signaling pathway, >>VEGF signaling pathway, >>Focal adhesion, >>Leukocyte transendothelial migration, >>Regulation of actin cytoskeleton, >>Bacterial invasion of epithelial cells, >>Shigellosis, >>Yersinia infection, >>Human cytomegalovirus infection, >>Human papillomavirus infection, >>Human immunodeficiency virus 1 infection, >>Viral carcinogenesis, >>Proteoglycans in cancer |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,ELISA |
| Conjugation | Unconjugated |
| Dilution range | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Paxillin. AA range:144-193 |
| Concentration | 1 mg/ml |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Assay type | Antibody validation/application |
| Expression system | Brain,Epithelium,Lung,Placenta,T-cell,Uterus, |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Mouse | |||||||
| Rat |
| Species | Dilution | Notes |
|---|---|---|
| Human | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. | — |
| Mouse | — | — |
| Rat | — | — |
| Species | Dilution | Notes |
|---|
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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