PLCB4 rabbit pAb from ELK Biotechnology Read more ›
PLCB4 rabbit pAb is a research-use antibody from ELK Biotechnology for studying PLCB4 in WB, ELISA workflows with listed reactivity for Human, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals in the retina. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2010],
| Specificity | PLCB4 Polyclonal Antibody detects endogenous levels of protein. |
|---|---|
| Validation evidence captions | Western Blot analysis of HEK293 lysis, using primary antibody at 1:1000 dilution. Secondary antibody(catalog#:RS23920) was diluted at 1:10000 |
| Collaborator | ELK Biotechnology |
| Partner model | ES10734 |
| Target | PLCB4 |
| Research areas | >>Inositol phosphate metabolism, >>Metabolic pathways, >>Rap1 signaling pathway, >>Calcium signaling pathway, >>cGMP-PKG signaling pathway, >>Chemokine signaling pathway, >>Phosphatidylinositol signaling system, >>Sphingolipid signaling pathway, >>Phospholipase D signaling pathway, >>Adrenergic signaling in cardiomyocytes, >>Vascular smooth muscle contraction, >>Wnt signaling pathway, >>Apelin signaling pathway, >>Gap junction, >>Platelet activation, >>Neutrophil extracellular trap formation, >>NOD-like receptor signaling pathway, >>Circadian entrainment, >>Long-term potentiation, >>Retrograde endocannabinoid signaling, >>Glutamatergic synapse, >>Cholinergic synapse, >>Serotonergic synapse, >>Dopaminergic synapse, >>Long-term depression, >>Taste transduction, >>Inflammatory mediator regulation of TRP channels, >>Insulin secretion, >>GnRH signaling pathway, >>Estrogen signaling pathway, >>Melanogenesis, >>Thyroid hormone synthesis, >>Thyroid hormone signaling pathway, >>Oxytocin signaling pathway, >>Glucagon signaling p |
| Reactivity | Human,Rat |
| Applications | WB,ELISA |
| Conjugation | Unconjugated |
| Dilution range | WB 1:500-2000 ELISA 1:5000-20000 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Concentration | 1 mg/ml |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Assay type | Antibody validation/application |
| Expression system | Preferentially expressed in the retina. |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat |
| Species | Dilution | Notes |
|---|---|---|
| Human | WB 1:500-2000 ELISA 1:5000-20000 | — |
| Rat | — | — |
| Species | Dilution | Notes |
|---|
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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