Collaborator ELK Biotechnology
Recombinant ProteinsISO 9001:2015
ABM100944

Recombinant Mouse TFF2 (C-6His)

ISO 9001|ABMIUM Verified™|Protein

Recombinant Mouse TFF2 (C-6His) from ELK Biotechnology Read more ›

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Product Description

Recombinant Mouse TFF2 (C-6His) is a research-use recombinant protein from ELK Biotechnology preparation representing TFF2 supplied as Lyophilized. Review the expression, purity, formulation and storage specifications below before selecting it for an assay or functional workflow.

Description

Recombinant Mouse Trefoil Factor 2 is produced by our Mammalian expression system and the target gene encoding Glu24-Tyr129 is expressed with a 6His tag at the C-terminus.

Background

Recombinant Murine TFF-2 is an 11.9 kDa polypeptide of 106 amino acid residues, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds. The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid secretion. Recent data suggests a potential role for TFF2 in acute and chronic asthma. It inhibits gastrointestinal motility and gastric acid secretion. As a structural component of gastric mucus, it possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains.

Handling information

Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100µg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Delivery condition The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Key Facts

Product typeRecombinant Proteins Target: TFF2
Collaborator ELK Biotechnology
Partner model EPT220
Target TFF2
Research areasMolecular Biology
Reactivity Product QC:C
Applications Protein research
Assay type Recombinant protein
Purity >95% by SDS-PAGE
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
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Validation Matrix

1 category
ABMIUM Validated™ ABMIUM Verified™ Expected Performance Not suitable
CategoryPurityEndotoxinBioactivity
Product QC

Specifications

Target
TFF2
Also known as
Trefoil Factor 2; Spasmolytic polypeptide; SP; Tff2; Sml1; Sp
Purity
>95% by SDS-PAGE
Form / buffer
Lyophilized

Storage & Stability

Long-term storage
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Compliance & Certifications

ABMIUM
ABMIUM Verified

Collaborator meets ABMIUM quality standards and overall product performance standards have been met.

ISO
ISO 9001

Quality management certification.

RUO
Research Use Only

For research applications. Not for diagnostic use.

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