ABM92584
MLKL (8H7) Mouse mAb
ISO 9001|ABMIUM Verified™|Antibody
MLKL (8H7) Mouse mAb from ELK Biotechnology Read more ›
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Product Description
MLKL (8H7) Mouse mAb is an ELK Biotechnology antibody for research workflows involving MLKL (8H7).
Background
Mixed lineage kinase domain-like protein (MLKL) is a pseudokinase that was identified as downstream target of RIP3 in the necroptosis pathway. During necroptosis RIP3 is phosphorylated at Ser227, which recruits MLKL and leads to its phosphorylation at Thr357 and Ser358.
Additional antibody information
| Validation evidence captions | Immunohistochemical analysis of paraffin-embedded Human Tonsil Tissue using MLKL（EM1328）Mouse mAb diluted at 1:200.. | Immunohistochemical analysis of paraffin-embedded Human Skin Tissue using MLKL（EM1328）Mouse mAb diluted at 1:200. |
|---|
Key Facts
Product type
Primary Antibody›
Target: MLKL (8H7)
| Target | MLKL (8H7) |
| Also known as | Mixed lineage kinase domain like protein, FLJ34389 |
| Concentration | 1mg/mL |
| Working concentration | IHC 1:100-200 |
| Species reactivity | Human |
| Observed band | 54kDa |
| Cellular localization | Cell membrane, Cytoplasm, Membrane |
| Form / buffer | Antibody solution |
| Research area | Antibody Research |
| Host species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Tested applications |
IHC |
| Dilution range | IHC 1:100-200 |
| Immunogen | Synthetic Peptide |
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Citations
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Reactivity & Application Validation
1 species| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human |
ABMIUM Validated™
IHC
| Species | Dilution | Notes |
|---|---|---|
| Human | IHC 1:100-200 | — |
Specifications
Target
MLKL (8H7)
Also known as
Mixed lineage kinase domain like protein, FLJ34389
Concentration
1mg/mL
Working concentration
IHC 1:100-200
Form / buffer
Antibody solution
Host species
Mouse
Clonality
Monoclonal
Isotype
IgG1
Conjugation
Unconjugated
Species reactivity
Human
Tested applications
IHC
Immunogen
Synthetic Peptide
Observed band
54kDa
Cellular localization
Cell membrane, Cytoplasm, Membrane
Dilution range
IHC 1:100-200
Storage & Stability
Avoid repeated freeze-thaw cycles.
Long-term storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Storage conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Compliance & Certifications
ISO 9001
ISO 9001:2015 Certified
Manufactured under ISO 9001:2015 quality management standards.
RUO
For Research Use Only
Not intended for diagnostic or therapeutic use.
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