CK19 Mouse mAb
CK19 Mouse mAb from ELK Biotechnology Read more ›
Product Description
CK19 Mouse mAb is an ELK Biotechnology antibody for research workflows involving CK19.
Background
This protein is a member of the keratin family. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Keratin 19 is not expressed in hepatocytes, therefore, antibody to keratin 19 is useful in the identification of liver metastasis. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours. Keratin 19 is often co-expressed with keratin 7.
Additional antibody information
| Validation evidence captions | IHC staining of human colon cancer tissue with CK19 mouse mAb(11F5) diluted at 1:200. |
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Key Facts
| Target | CK19 |
| Also known as | Cytokeratin 19, K19, K1CS, keratin 19, KRT19 |
| Concentration | 1mg/mL |
| Working concentration | IHC 1:200 |
| Species reactivity | Human, Rat, Mouse |
| Observed band | 44kDa |
| Cellular localization | Cytoskeleton,Cytosol |
| Form / buffer | Antibody solution |
| Research area | Antibody Research |
| Host species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Tested applications |
IHC |
| Dilution range | IHC 1:200 |
| Immunogen | Synthetic Peptide |
Reactivity & Application Validation
3 speciess| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
| Species | Dilution | Notes |
|---|---|---|
| Human | IHC 1:200 | — |
| Rat | — | — |
| Mouse | — | — |
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.