CK19 Mouse mAb from ELK Biotechnology Read more ›
CK19 Mouse mAb is a research-use antibody from ELK Biotechnology for studying CK19 in IHC workflows with listed reactivity for Human, Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.
This protein is a member of the keratin family. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Keratin 19 is not expressed in hepatocytes, therefore, antibody to keratin 19 is useful in the identification of liver metastasis. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours. Keratin 19 is often co-expressed with keratin 7.
| Validation evidence captions | IHC staining of human colon cancer tissue with CK19 mouse mAb(11F5) diluted at 1:200. |
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| Collaborator | ELK Biotechnology |
| Partner model | EM1051 |
| Target | CK19 |
| Research areas | Antibody Research |
| Reactivity | Human,Rat,Mouse |
| Applications | IHC |
| Conjugation | Unconjugated |
| Dilution range | IHC 1:200 |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Immunogen | Synthetic Peptide |
| Concentration | 1mg/mL |
| Assay type | Antibody validation/application |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
| Species | Dilution | Notes |
|---|---|---|
| Human | IHC 1:200 | — |
| Rat | — | — |
| Mouse | — | — |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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