ATG4b Rabbit pAb
ATG4b Rabbit pAb from ELK Biotechnology Read more ›
Product Description
ATG4b Rabbit pAb is an ELK Biotechnology antibody for research workflows involving ATG4b.
Background
Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. Control of autophagy was largely discovered in yeast and involves proteins encoded by a set of autophagy-related genes (Atg). Formation of autophagic vesicles requires a pair of essential ubiquitin-like conjugation systems, Atg12-Atg5 and Atg8-phosphatidylethanolamine (Atg8-PE), which are widely conserved in eukaryotes. Numerous mammalian counterparts to yeast Atg proteins have been described, including three Atg8 proteins (GATE-16, GABARAP, and LC3) and four Atg4 homologs (Atg4A/autophagin-2, Atg4B/autophagin-1, Atg4C/autophagin-3, and Atg4D/autophagin-4).
Additional antibody information
| Validation evidence captions | Immunohistochemical analysis of paraffin-embedded Human Skeletal Muscle Tissue using ATG4b （EA348）Rabbit pAb diluted at 1:200 | Immunohistochemical analysis of paraffin-embedded Human Brain Tissue using ATG4b （EA348）Rabbit pAb diluted at 1:200 |
|---|
Key Facts
| Target | ATG4b |
| Also known as | APG4B, Autl1,Cysteine protease ATG4B antibody |
| Concentration | 1mg/mL |
| Working concentration | IHC 1:100-200 |
| Species reactivity | Human, Mouse, Rat |
| Observed band | 44kDa |
| Cellular localization | Cytoplasm |
| Form / buffer | Antibody solution |
| Research area | Antibody Research |
| Host species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Tested applications |
IHC |
| Dilution range | IHC 1:100-200 |
| Immunogen | Recombinant Protein |
Reactivity & Application Validation
3 speciess| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Mouse | |||||||
| Rat |
| Species | Dilution | Notes |
|---|---|---|
| Human | IHC 1:100-200 | — |
| Mouse | — | — |
| Rat | — | — |
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.