ATM Rabbit pAb from ELK Biotechnology
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ATM Rabbit pAb is a research-use antibody from ELK Biotechnology for studying ATM in IHC workflows with listed reactivity for Human, Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.
Ataxia telangiectasia mutated kinase (ATM) is a serine/threonine kinase that regulates cell cycle checkpoints and DNA repair. ATM kinase regulates a number of proteins involved in cell cycle checkpoint control, apoptosis, and DNA repair.
| Validation evidence captions | Immunohistochemical analysis of paraffin-embedded Human Colon Carcinoma Tissue using ATM（EA323）Rabbit pAb diluted at 1:500. | Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma Tissue using ATM（EA323）Rabbit pAb diluted at 1:500. | Immunohistochemical analysis of paraffin-embedded Human Prostate Carcinoma Tissue using ATM（EA323）Rabbit pAb diluted at 1:200. |
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Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
ATM (ATM serine/threonine kinase), also known as serine-protein kinase ATM and A-T mutated, is a central DNA-damage-response kinase activated by DNA double-strand breaks. It coordinates checkpoint signaling and genome-stability responses while ABMIUM products below provide catalogue-backed reagents for ATM research.
Biological function: ATM is a large serine/threonine protein kinase that functions as a DNA damage sensor and signaling hub. Following DNA double-strand breaks and other genotoxic stresses, ATM phosphorylates downstream checkpoint and repair factors to coordinate cell-cycle control, DNA repair, chromatin responses and stress signaling.
