IκB α Rabbit pAb from ELK Biotechnology Read more ›
IκB α Rabbit pAb is a research-use antibody from ELK Biotechnology for studying IκB α in WB, IHC workflows with listed reactivity for Human, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines.
| Validation evidence captions | Western blot analysis of 1) Hela, 2)PC12 with IκB α Rabbit pAb EA213 diluted at 1:2,000. | Immunohistochemical analysis of paraffin-embedded Human KidneyTissue using I κB α （EA213）Rabbit pAb diluted at 1:500. |
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| Collaborator | ELK Biotechnology |
| Partner model | EA213 |
| Target | IκB α |
| Research areas | Antibody Research |
| Reactivity | Human,Rat |
| Applications | WB,IHC |
| Conjugation | Unconjugated |
| Dilution range | WB 1:2,000-5,000 IHC 1:200-500 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant Protein |
| Concentration | 1mg/mL |
| Assay type | Antibody validation/application |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat |
| Species | Dilution | Notes |
|---|---|---|
| Human | WB 1:2 | — |
| Rat | — | — |
| Species | Dilution | Notes |
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Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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