Lamin B1 Rabbit pAb
Lamin B1 Rabbit pAb from ELK Biotechnology Read more ›
Product Description
Lamin B1 Rabbit pAb is an ELK Biotechnology antibody for research workflows involving Lamin B1.
Background
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.
Additional antibody information
| Validation evidence captions | Western blot analysis of 1) 293T, 2)Mouse Brain, 3) Rat Brain tissue with EA041 diluted at 1:2,000. | Immunohistochemical analysis of paraffin-embedded Mouse Kidney Tissue using Lamin B1 (EA041) Rabbit pAb diluted at 1:500. |
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Key Facts
| Target | Lamin B1 |
| Also known as | ADLD, LMB1,LMNB1, MGC111419, OTTHUMP00000159218 |
| Concentration | 1mg/mL |
| Working concentration | WB 1:1,000-3,000 IHC: 1:500-1,000 |
| Species reactivity | Human, Rat, Mouse |
| Observed band | 68,45kDa |
| Cellular localization | Mitochondrion inner membrane |
| Form / buffer | Antibody solution |
| Research area | Antibody Research |
| Host species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Tested applications |
WBIHC |
| Dilution range | WB 1:1,000-3,000 IHC: 1:500-1,000 |
| Immunogen | Recombinant Protein |
Reactivity & Application Validation
3 speciess| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
| Species | Dilution | Notes |
|---|---|---|
| Human | WB 1:1 | — |
| Rat | — | — |
| Mouse | — | — |
| Species | Dilution | Notes |
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Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.