MeCP2 Rabbit pAb
MeCP2 Rabbit pAb from ELK Biotechnology Read more ›
Product Description
MeCP2 Rabbit pAb is an ELK Biotechnology antibody for research workflows involving MeCP2.
Background
Methyl-CpG-binding protein 2(MeCP2), whose exact function is unclear. It appears to help regulate gene activity (expression) by modifying chromatin, the complex of DNA and protein that packages DNA into chromosomes. The MeCP2 protein usually regulates genes involved in brain function, even though this protein is found throughout the body.Within the brain, the MeCP2 protein is important for the function of nerve cells (neurons) and is present in high levels in mature neurons. This protein likely plays a role in maintaining connections (synapses) between neurons, where cell-to-cell communication occurs. Many of the genes that are known to be regulated by the MeCP2 protein play a role in normal brain function, particularly the maintenance of synapses.
Additional antibody information
| Validation evidence captions | Western blot analysis of Hela with MeCP2 Rabbit pAb diluted at 1, 1:2,000 2, 1:5,000 |
|---|
Key Facts
| Target | MeCP2 |
| Also known as | Methyl CpG Binding Protein 2 ;RTS; AUTSX3; MRX16; MRX79; PPMX; RTT; Rett Syndrome; Mental Retardation,X-linked 16 |
| Concentration | 1mg/mL |
| Working concentration | WB 1:2,000 |
| Species reactivity | Human |
| Observed band | 53kDa |
| Cellular localization | Nucleus |
| Form / buffer | Antibody solution |
| Research area | Antibody Research |
| Host species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Tested applications |
WB |
| Dilution range | WB 1:2,000 |
| Immunogen | Synthetic Peptide |
Reactivity & Application Validation
1 species| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human |
| Species | Dilution | Notes |
|---|---|---|
| Human | WB 1:2 | — |
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.