Primary Antibody supplied by Boster Bio Read more ›
Anti-p27Kip1 CDKN1B Antibody (Monoclonal, DCS-72) is a research-use antibody from Boster Bio for studying Cyclin-dependent kinase inhibitor 1B in IF/ICC, WB workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.
Boster Bio Anti-p27Kip1 CDKN1B Antibody (Monoclonal, DCS-72) catalog # MA1076. Tested in ICC, WB applications. This antibody reacts with Human, Mouse, Rat.P27 (kip1), also known as cyclin dependent kinase inhibitor 1B (CDKN1B), is a major target of AFX-like forkhead proteins. CDKN1B (p27) belongs to the Cip/Kip family and functions as an important cell cycle gatekeeper. Phosphorylation leads to the ubiquitination and degradation of CDKN1B. P27 (kip1) mapped to 12p13. An increase in p27 causes proliferating cells to exit from the cell cycle, and a decrease in p27 is necessary for quiescent cells to resume division. Abnormally low amounts of p27 are associated with pathological states of excessive cell proliferation, especially cancers. Overexpression of p27Kip1 lengthens the G1 phase in a mouse model that targets inducible gene expression to central nervous system progenitor cells.
| Collaborator | Boster Bio |
| Partner model | MA1076 |
| Target | Cyclin-dependent kinase inhibitor 1B |
| Reactivity | Human,Mouse,Rat |
| Applications | IF/ICC,WB |
| Conjugation | Unconjugated |
| Cross-reactivity | No cross-reactivity with other proteins |
| Dilution range | Immunocytochemistry , 1μg/ml, Human, mouse, rat, -<br>Western blot, 2-4μg/ml, Human, mouse, rat<br> |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | Clone: DCS-72 |
| Isotype | Mouse IgG1 |
| Immunogen | recombinant rodent p27Kip1 protein. |
| Concentration | Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml. |
| Purification | Ascites |
| Purity | No cross reactivity with other proteins. |
| Shelf life | Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles. |
| Availability | Available |
| Species | WB | IHC | IHC-P | IHC-F | IF/ICC | Flow Cytometry | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Mouse | ||||||||
| Rat |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
For research applications. Not for diagnostic use.
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