Manufactured by:Boster Bio
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Anti-IL1RA Antibody (monoclonal, 12C13

Primary Antibody supplied by Boster Bio

SKU:
ABM23808-1
Manufacturer SKU
M00651-1
Product type
Primary Antibodies
TargetInterleukin-1 receptor antagonist protein
ApplicationsELISA, Flow Cytometry, IHC, IHC-P, WB
Species / reactivityRat

Manufacturer provenance

Manufactured by:
Boster Bio
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Anti-IL1RA Antibody (monoclonal, 12C13 is a research-use antibody from Boster Bio for studying Interleukin-1 receptor antagonist protein in ELISA, Flow Cytometry, IHC, IHC-P, WB workflows with listed reactivity for Rat. Specifications and supporting documents below should be reviewed when planning the experiment.

Boster Bio Anti-IL1RA Antibody Picoband® (monoclonal, 12C13) catalog # M00651-1. Tested in ELISA applications. This antibody reacts with Rat.

The interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene. The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.

Product information

Key facts & specifications
Also known as
Anakinra; ICIL 1RA; IL 1ra; IL 1ra3; IL 1RN; IL1 inhibitor; IL1F3; IL1RA; IL-1RA; IL1RN; IRAP; IL-1RN
Host species
Mouse
Clonality
Monoclonal
Clone number
Clone: 12C13
Isotype
Mouse IgG2b
Cross-reactivity
No cross-reactivity with other proteins.
Dilution range
ELISA (Cap), 1-5μg/ml, Rat
Immunogen
E. coli-derived rat IL1RA recombinant protein (Position: H27-Q178). Rat IL1RA shares 77.6% and 90.7% amino acid (aa) sequence identity with human and mouse IL1RA, respectively.
Observed band
100-110 kDa
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Purification
Immunogen affinity purified.
Form / buffer
Lyophilized
Sequence fragment
E. coli-derived rat IL1RA recombinant protein (Position: H27-Q178). Rat IL1RA shares 77.6% and 90.7% amino acid (aa) sequence identity with human and mouse IL1RA, respectively.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIP
Rat
Identifiers & database references
Manufacturer SKU
M00651-1
Gene symbol
Il1rn
Gene ID
60582
UniProt accession
P25086
Storage, stability & shipping
Shelf life
Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.
Storage conditions
Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.
Shipped at
Ambient or cold-chain dependent on product format
Short-term storage
Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.
Long-term storage
Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.
Storage buffer
Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.
Storage warning
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Compliance & documents
CE marked
No
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

IL1RNinterleukin 1 receptor antagonist

View target guide

IL1RN identifies interleukin 1 receptor antagonist in Homo sapiens (Human). This target record connects NCBI Gene 3557, UniProtKB P18510 and related ABMIUM catalogue products.

Biological function: IL1RN is an anti-inflammatory interleukin-1 receptor antagonist that counteracts IL1A- and IL1B-driven signalling and helps limit excessive inflammatory responses.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
3557
UniProtKB
P18510
Boster Bio
£328.00£278.80