Manufactured by:BT LAB
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Human Leukocyte-associated Immunoglobulin-like Receptor 2, LAIR2 ELISA Kit

Human Leukocyte-associated Immunoglobulin-like Receptor 2, LAIR2 ELISA Kit

SKU:
ABM216890
Manufacturer SKU
E5576Hu
Product type
ELISA Kits
TargetLAIR2
ApplicationsELISA
Species / reactivityHuman
Sample typeSerum, Plasma, Cell culture supernatants, Ascites, Tissue homogenates

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

Leukocyte-associated immunoglobulin-like receptor 2 is a protein that in humans is encoded by the LAIR2 gene. The protein encoded by this gene is a member of the immunoglobulin superfamily. It was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily, including LAIR1. The function of this protein is unknown, although it is thought to be secreted and may help modulate mucosal tolerance. Two transcript variants encoding different isoforms have been found for this gene.

Test principle

This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with Human LAIR2 antibody. LAIR2 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human LAIR2 Antibody is added and binds to LAIR2 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated LAIR2 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human LAIR2. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Key facts & specifications
Research areas
Immunology
Also known as
CD antigen CD306;CD306;LAIR2;LAIR-2;Leukocyte-associated immunoglobulin-like receptor 2
Assay type
Sandwich
Detection method
Colorimetric (450 nm)
Sensitivity
9.75ng/L
Detection range
20-4500ng/L
Plate format
Pre-coated ELISA plate
Assay duration
1h 30m
Molecular weight
16,280 Da
Quantity per pack
48T, 96T
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceSerumPlasmaCell culture supernatantsAscitesTissue homogenates
Compatibility
Identifiers & database references
Manufacturer SKU
E5576Hu
Gene symbol
LAIR2
Gene ID
3904
UniProt accession
Q6ISS4
Storage, stability & shipping
Shelf life
Store at -20°C for one year. Or store at 2-8°C for 6 months. If individual reagents are opened it is recommended that the kit be used within 1 month. Avoid repeated thaw cycles. *This product is for research use only, not for use in diagnosis procedures. It’s highly recommended to read this instruction entirely before use.
Storage conditions
2-8ºC
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

LAIR2leukocyte associated immunoglobulin like receptor 2

View target guide

LAIR2 identifies leukocyte associated immunoglobulin like receptor 2 in Homo sapiens (Human). This target record connects NCBI Gene 3904, UniProtKB Q6ISS4 and related ABMIUM catalogue products.

Organism
Homo sapiens (Human)
NCBI Gene
3904
UniProtKB
Q6ISS4
BT LAB
£240.93£205.00