Manufactured by:BT LAB
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CASP6 Monoclonal Antibody

CASP6 Monoclonal Antibody

SKU:
ABM204673
Manufacturer SKU
BT-MCA3911
Product type
Primary Antibodies
TargetCASP6
ApplicationsWB, Flow Cytometry, ELISA

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.

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Key facts & specifications
Research areas
Neuroscience
Also known as
MCH2
Host species
Mouse
Clonality
Monoclonal
Isotype
Mouse IgG2a
Dilution range
WB: 1:500 - 1:2000; FCM: 1:200 - 1:400; ELISA: 1:10000
Immunogen
Purified recombinant fragment of human CASP6 (AA: 194–293) expressed in E. Coli.
Molecular weight
33.3kDa
Quantity per pack
100μL, 50μL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBFCMELISA
Applications
Identifiers & database references
Manufacturer SKU
BT-MCA3911
Gene ID
839
UniProt accession
P55212
Storage, stability & shipping
Storage conditions
Store at 4°C short term. Aliquot and store at -20°C long term.
Short-term storage
Store at 4°C short term.
Long-term storage
Aliquot and store at -20°C long term.
Storage buffer
Purified antibody in PBS with 0.05% sodium azide
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

CASP6caspase 6

View target guide

CASP6 identifies caspase 6 in Homo sapiens (Human). This target record connects NCBI Gene 839, UniProtKB P55212 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
839
UniProtKB
P55212
BT LAB
£240.93£205.00