Manufactured by:BT LAB
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GZMB Monoclonal Antibody

GZMB Monoclonal Antibody

SKU:
ABM202167
Manufacturer SKU
BT-MCA2658
Product type
Primary Antibodies
TargetGZMB
ApplicationsWB, IHC-P, ELISA, IHC

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]

Key facts & specifications
Research areas
Others
Also known as
C11;HLP;CCPI;CGL1;CSPB;SECT;CGL-1;CSP-B;CTLA1;CTSGL1
Host species
Mouse
Clonality
Monoclonal
Isotype
Mouse IgG2a
Dilution range
WB: 1:500 - 1:2000; IHC-p: 1:200-1:1000; ELISA: 1:10000
Immunogen
Purified recombinant fragment of human GZMB (AA: 21-247) expressed in E. Coli.
Molecular weight
28kDa
Quantity per pack
100μL, 50μL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBIHC-pELISAIHC
Applications
Identifiers & database references
Manufacturer SKU
BT-MCA2658
Gene ID
3002
UniProt accession
P10144
Storage, stability & shipping
Storage conditions
Store at 4°C short term. Aliquot and store at -20°C long term.
Short-term storage
Store at 4°C short term.
Long-term storage
Aliquot and store at -20°C long term.
Storage buffer
Purified antibody in PBS with 0.05% sodium azide
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

GZMBgranzyme B

View target guide

GZMB identifies granzyme B in Homo sapiens (Human). This target record connects NCBI Gene 3002, UniProtKB P10144 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
3002
UniProtKB
P10144
BT LAB
£240.93£205.00