Manufactured by:BT LAB
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GRK 2 Monoclonal Antibody

GRK 2 Monoclonal Antibody

SKU:
ABM199670
Manufacturer SKU
BT-MCA0630
Product type
Primary Antibodies
TargetADRBK1
ApplicationsELISA, IF/ICC, IHC, WB, IHC-P
Species / reactivityHuman, Mouse, Rat, Monkey

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Background

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

Key facts & specifications
Research areas
Signal Transduction, Neuroscience
Also known as
ADRBK1; BARK; BARK1; GRK2; Beta-adrenergic receptor kinase 1; Beta-ARK-1; G-protein coupled receptor kinase 2
Host species
Mouse
Clonality
Monoclonal
Isotype
IgG
Dilution range
ELISA: 1:10000; IF: 1:200 - 1:1000; IHC: 1:200 - 1:1000; WB: 1:500 - 1:2000
Immunogen
Purified recombinant fragment of human GRK 2 expressed in E. Coli.
Concentration
1 mg/ml
Purification
Affinity purification
Quantity per pack
50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceELISAIFIHCWBIHC-pICC
Applications
Identifiers & database references
Manufacturer SKU
BT-MCA0630
Gene ID
15625238
UniProt accession
P25098
Storage, stability & shipping
Shelf life
-20°C for one year
Storage conditions
-20°C for one year
Storage buffer
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

GRK2G protein-coupled receptor kinase 2

View target guide

GRK2 identifies G protein-coupled receptor kinase 2 in Homo sapiens (Human). This target record connects NCBI Gene 156, UniProtKB P25098 and related ABMIUM catalogue products.

Organism
Homo sapiens (Human)
NCBI Gene
156
UniProtKB
P25098
BT LAB
£135.52£115.00