Manufactured by:BT LAB
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Trk A(Phospho Tyr757) Polyclonal Antibody

Trk A(Phospho Tyr757) Polyclonal Antibody

SKU:
ABM196541
Manufacturer SKU
BT-AP15156
Product type
Primary Antibodies
TargetNTRK1
ApplicationsIHC-P, ELISA, IF/ICC
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

Key facts & specifications
Research areas
Neuroscience, Cancer, Metabolism
Also known as
High affinity nerve growth factor receptor; NTRK1; MTC; TRK; TRKA; High affinity nerve growth factor receptor; Neurotrophic tyrosine kinase receptor type 1; TRK1-transforming tyrosine kinase protein; Tropomyosin-related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A;
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
IHC-p: 1: 100 - 1: 300; ELISA: 1: 10000
Immunogen
The antiserum was produced against synthesized peptide derived from human Trk A around the phosphorylation site of Tyr757. AA range:726-775
Molecular weight
87497
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceIHC-pELISAIF
Applications
Identifiers & database references
Manufacturer SKU
BT-AP15156
Gene ID
4914
UniProt accession
P04629
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

NTRK1neurotrophic receptor tyrosine kinase 1

View target guide

NTRK1 identifies neurotrophic receptor tyrosine kinase 1 in Homo sapiens (Human). This target record connects NCBI Gene 4914, UniProtKB P04629 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
4914
UniProtKB
P04629
BT LAB
£81.31£69.00