Manufactured by:BT LAB
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Ret(Phospho Tyr1015) Polyclonal Antibody

Ret(Phospho Tyr1015) Polyclonal Antibody

SKU:
ABM192308
Manufacturer SKU
BT-AP13669
Product type
Primary Antibodies
TargetRET
ApplicationsWB, ELISA
Species / reactivityHuman, Mouse, Rat, Monkey

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed.

Key facts & specifications
Research areas
Cancer, Signal Transduction
Also known as
Proto-oncogene tyrosine-protein kinase receptor Ret; RET; CDHF12; CDHR16; PTC; RET51; Proto-oncogene tyrosine-protein kinase receptor Ret; Cadherin family member 12; Proto-oncogene c-Ret
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; ELISA: 1: 5000
Immunogen
The antiserum was produced against synthesized peptide derived from human Ret around the phosphorylation site of Tyr1015. AA range:991-1040
Molecular weight
124319
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBELISA
Applications
Identifiers & database references
Manufacturer SKU
BT-AP13669
Gene ID
5979
UniProt accession
P07949
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

RETret proto-oncogene

View target guide

RET identifies ret proto-oncogene in Homo sapiens (Human). This target record connects NCBI Gene 5979, UniProtKB P07949 and related ABMIUM catalogue products.

Organism
Homo sapiens (Human)
NCBI Gene
5979
UniProtKB
P07949
BT LAB
£81.31£69.00