Manufactured by:BT LAB
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PAK alpha(Phospho Ser199) Polyclonal Antibody

PAK alpha(Phospho Ser199) Polyclonal Antibody

SKU:
ABM189587
Manufacturer SKU
BT-AP12746
Product type
Primary Antibodies
TargetPAK1
ApplicationsWB, IHC-P, ELISA, IF/ICC
Species / reactivityHuman, Mouse, Rat, Monkey

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Key facts & specifications
Research areas
Cancer, Cell Biology, Signal Transduction
Also known as
Serine/threonine-protein kinase PAK 1; PAK1; Serine/threonine-protein kinase PAK 1; Alpha-PAK; p21-activated kinase 1; PAK-1; p65-PAK
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; IHC-p: 1: 100 - 1: 300; ELISA: 1: 10000
Immunogen
The antiserum was produced against synthesized peptide derived from human PAK1 around the phosphorylation site of Ser199. AA range:165-214
Molecular weight
60647
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBIHC-pELISAIF
Applications
Identifiers & database references
Manufacturer SKU
BT-AP12746
Gene ID
5058
UniProt accession
Q13153
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

PAK1p21 (RAC1) activated kinase 1

View target guide

PAK1 identifies p21 (RAC1) activated kinase 1 in Homo sapiens (Human). This target record connects NCBI Gene 5058, UniProtKB Q13153 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
5058
UniProtKB
Q13153
BT LAB
£81.31£69.00