Manufactured by:BT LAB
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MerTK/Tyro3(Phospho Tyr749/681) Polyclonal Antibody

MerTK/Tyro3(Phospho Tyr749/681) Polyclonal Antibody

SKU:
ABM185221
Manufacturer SKU
BT-AP11288
Product type
Primary Antibodies
TargetMERTK
ApplicationsWB, IHC-P, ELISA, IF/ICC
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

Key facts & specifications
Research areas
Neuroscience, Signal Transduction
Also known as
Tyrosine-protein kinase Mer/Tyrosine-protein kinase receptor TYRO3; MERTK; MER; Tyrosine-protein kinase Mer; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK; TYRO3; BYK; DTK; RSE; SKY; Tyrosine-protein kinase receptor TYRO3; Tyrosine-protein kinase DTK; Tyrosine-protein kinase RSE; Tyrosine-protein kin
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; IHC-p: 1: 100 - 1: 300; ELISA: 1: 10000
Immunogen
The antiserum was produced against synthesized peptide derived from human MER/SKY around the phosphorylation site of Tyr749/681. AA range:716-765
Molecular weight
110249;96905
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBIHC-pELISAIF
Applications
Identifiers & database references
Manufacturer SKU
BT-AP11288
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

MERTKMER proto-oncogene, tyrosine kinase

View target guide

MERTK identifies MER proto-oncogene, tyrosine kinase in Homo sapiens (Human). This target record connects NCBI Gene 10461, UniProtKB Q12866 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
10461
UniProtKB
Q12866
BT LAB
£81.31£69.00