Manufactured by:BT LAB
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PR(Phospho Ser190) Polyclonal Antibody

PR(Phospho Ser190) Polyclonal Antibody

SKU:
ABM174472
Manufacturer SKU
BT-AP07671
Product type
Primary Antibodies
TargetPGR
ApplicationsWB, IHC-P, ELISA, IF/ICC
Species / reactivityHuman, Monkey

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.

Key facts & specifications
Research areas
Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Signal Transduction
Also known as
Progesterone receptor; PGR; NR3C3; Progesterone receptor; PR; Nuclear receptor subfamily 3 group C member 3
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; IHC-p: 1: 100 - 1: 300; ELISA: 1: 20000
Immunogen
The antiserum was produced against synthesized peptide derived from human Progesterone Receptor around the phosphorylation site of Ser190. AA range:161-210
Molecular weight
98981
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBIHC-pELISAIF
Applications
Identifiers & database references
Manufacturer SKU
BT-AP07671
Gene ID
5241
UniProt accession
P06401
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

PGRprogesterone receptor

View target guide

PGR identifies progesterone receptor in Homo sapiens (Human). This target record connects NCBI Gene 5241, UniProtKB P06401 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
5241
UniProtKB
P06401
BT LAB
£81.31£69.00