Macroglobulin Alpha-2 Polyclonal Antibody
Know who made it. See the evidence. Buy through one marketplace.
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Evidence | WB | IHC-p | ELISA |
|---|---|---|---|
| Applications |
This product is manufactured by BT LAB and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
Alpha-2-macroglobulin (A2M) is a large circulating plasma protein that functions as a broad-spectrum protease inhibitor. This catalogue-backed target record links A2M nomenclature, identifiers, aliases and ABMIUM products.
Biological function: Alpha-2-macroglobulin (A2M) inhibits multiple classes of proteases through a bait-region trapping mechanism. Protease cleavage induces a conformational change that encloses the enzyme; A2M also binds and transports a range of cytokines and growth factors.
