Manufactured by:BT LAB
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IGF-IR Polyclonal Antibody

IGF-IR Polyclonal Antibody

SKU:
ABM164869
Manufacturer SKU
BT-AP04398
Product type
Primary Antibodies
TargetIGF1R
ApplicationsWB, IHC, ELISA, IHC-P
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Background

IGF1R, this receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Key facts & specifications
Research areas
Signal Transduction
Also known as
IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; IHC: 1: 100 - 1: 300; ELISA: 1: 40000
Immunogen
The antiserum was produced against synthesized peptide derived from human IGF1R. AA range:1311-1360
Molecular weight
154793
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBIHCELISAIHC-p
Applications
Identifiers & database references
Manufacturer SKU
BT-AP04398
Gene ID
3480
UniProt accession
P08069
Storage, stability & shipping
Shelf life
-20°C for one year
Storage conditions
-20°C for one year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

IGF1Rinsulin like growth factor 1 receptor

View target guide

IGF1R identifies insulin like growth factor 1 receptor in Homo sapiens (Human). This target record connects NCBI Gene 3480, UniProtKB P08069 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
3480
UniProtKB
P08069
BT LAB
£81.31£69.00