Manufactured by:BT LAB
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GLI-3 Polyclonal Antibody

GLI-3 Polyclonal Antibody

SKU:
ABM162421
Manufacturer SKU
BT-AP03582
Product type
Primary Antibodies
TargetGLI3
ApplicationsIHC, IF/ICC, ELISA, IHC-P
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

GLI3 encodes GLI family zinc finger 3 which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.

Key facts & specifications
Research areas
Epigenetics and Nuclear Signaling
Also known as
GLI3; Transcriptional activator GLI3; GLI3 form of 190 kDa; GLI3-190; GLI3 full length protein; GLI3FL
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
IHC: 1: 100 - 1: 300; IF: 1: 200 - 1: 1000; ELISA: 1: 10000
Immunogen
The antiserum was produced against synthesized peptide derived from human GLI-3. AA range:11-60
Molecular weight
13553
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceIHCIFELISAIHC-p
Applications
Identifiers & database references
Manufacturer SKU
BT-AP03582
Gene ID
2737
UniProt accession
P10071
Storage, stability & shipping
Shelf life
-20°C for one year
Storage conditions
-20°C for one year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

BT LAB
£81.31£69.00