CX3CR1 Polyclonal Antibody
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Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. CX3C chemokine receptor 1 encoded by CX3CR1 is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in CX3CR1 lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.
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Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
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This product is manufactured by BT LAB and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
CX3CR1 identifies C-X3-C motif chemokine receptor 1 in Homo sapiens (Human). This target record connects NCBI Gene 1524, UniProtKB P49238 and related ABMIUM catalogue products.
