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AMPK alpha 1(Phospho-Ser485) Rabbit Polyclonal Antibody

AMPK alpha 1(Phospho-Ser485) Rabbit Polyclonal Antibody

SKU:
ABM152901
Manufacturer SKU
BT-AP00381
Product type
Primary Antibodies
TargetAMPK1
ApplicationsWB
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Key facts & specifications
Research areas
Cardiovascular, Signal Transduction, Cancer, Metabolism, Neuroscience, Epigenetics and Nuclear Signaling
Also known as
AMPKα1 (Ser485) ; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; EC 2.7.11.1; Acetyl-CoA carboxylase kinase; ACACA kinase; EC 2.7.11.27; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; EC 2.7.11.31; Tau-protein kinase PRKAA1; EC 2.7.11.26)
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 1000 - 1: 2000
Immunogen
Synthesized phosho peptide around human AMPKα1 (Ser485)
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Quantity per pack
100ul, 50ul, 20ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWB
Applications
Identifiers & database references
Manufacturer SKU
BT-AP00381
Gene ID
5562
UniProt accession
Q13131
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

PRKAA1protein kinase AMP-activated catalytic subunit alpha 1

View target guide

PRKAA1 identifies protein kinase AMP-activated catalytic subunit alpha 1 in Homo sapiens (Human). This target record connects NCBI Gene 5562, UniProtKB Q13131 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
5562
UniProtKB
Q13131
BT LAB
£207.05£176.00