Anti-Human CD14 Antibody [HCD14] with collaborator-tested evidence for Flow Cyt. Read more ›
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The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion.
Cluster of differentiation 14 (CD14) is a member of the CD system. It takes its name from its inclusion in the CD molecule surface marker proteins. CD14 exists in two forms: a form anchored into the membrane or a soluble form. CD14 was found expressed in macrophages, neutrophil granulocyte and dendritic cells. The major function is to serve as a co-receptor (along with TLR4 and MD-2) for the bacterial lipopolysaccharide (LPS) and other pathogen-associated molecular patterns.
Product profile: reactivity: Human; host: Mouse; clonality: Monoclonal; clone: HCD14; isotype: Mouse IgG1, κ; available conjugation options: Unconjugated.
Application evidence: Elabscience lists this product for FCM. In the ABMIUM matrix, these listed applications are marked C to show collaborator-tested ABMIUM Verified evidence. Applications not listed in the supplied data remain marked N.
Technical notes: immunogen: Recombinant Human CD14 protein; purification: >98%, Protein A/G purified; concentration: ≥ 1 mg/mL.
Database references: UniProt: P08571.
Research Use Only.
| Collaborator | Elabscience |
| Partner model | AN009350P_100mg |
| Target | CD14 |
| Research areas | Lysates, Stem Cells, Kits, Immunology, Other, CDs, Toll-like Receptor Signaling Pathway, TLR Signaling, Endothelial Progenitors Markers, Hematopoietic Stem Cell Markers, Mesenchymal Stem Cells |
| Reactivity | Human |
| Applications | Flow Cytometry |
| Conjugation | Unconjugated |
| Dilution range | FCM 2 μg/mL(0.5×10<sup>6</sup>-1×10<sup>6</sup> cells) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | HCD14 |
| Isotype | Mouse IgG1, κ |
| Immunogen | Recombinant Human CD14 protein |
| Concentration | ≥ 1 mg/mL |
| Purification | >98%, Protein A/G purified |
| Purity | >98% |
| Shelf life | 12 months from shipping dates |
| Availability | In stock - ships within 2 business days |
| Lead time | 2-3 business days |
| Species | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP |
|---|---|---|---|---|---|---|---|
| Human |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
Environmental management certification.
Occupational health and safety management certification.
For research applications. Not for diagnostic use.
REACH compliant.
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