Anti-Human CD14 Antibody [HCD14]
Anti-Human CD14 Antibody [HCD14] with collaborator-tested evidence for Flow Cyt. Read more ›
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Product Description
The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion.
Cluster of differentiation 14 (CD14) is a member of the CD system. It takes its name from its inclusion in the CD molecule surface marker proteins. CD14 exists in two forms: a form anchored into the membrane or a soluble form. CD14 was found expressed in macrophages, neutrophil granulocyte and dendritic cells. The major function is to serve as a co-receptor (along with TLR4 and MD-2) for the bacterial lipopolysaccharide (LPS) and other pathogen-associated molecular patterns.
Product profile: reactivity: Human; host: Mouse; clonality: Monoclonal; clone: HCD14; isotype: Mouse IgG1, κ; available conjugation options: Unconjugated.
Application evidence: Elabscience lists this product for FCM. In the ABMIUM matrix, these listed applications are marked C to show collaborator-tested ABMIUM Verified evidence. Applications not listed in the supplied data remain marked N.
Technical notes: immunogen: Recombinant Human CD14 protein; purification: >98%, Protein A/G purified; concentration: ≥ 1 mg/mL.
Database references: UniProt: P08571.
Research Use Only.
Key Facts
| Target | CD14 |
| Also known as | CD14, CD_antigen=CD14, LPS-R, membrane-bound form, Mo2, Monocyte differentiation antigen CD14 urinary form, Myeloid cell specific leucine rich glycoprotein, monocyte differentiation antigen CD, CD14, soluble, CD14 antigen, CD14 molecule, monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, LPS R |
| Concentration | ≥ 1 mg/mL |
| Species reactivity | Human |
| Purity | >98% |
| Shelf life | 12 months from shipping dates |
| Research area | Lysates, Stem Cells, Kits, Immunology, Other, CDs, Toll-like Receptor Signaling Pathway, TLR Signaling, Endothelial Progenitors Markers, Hematopoietic Stem Cell Markers, Mesenchymal Stem Cells |
| WB | IHC-P | IHC-FR | IF/ICC | FLOW CYT | IP | CHIP | |
|---|---|---|---|---|---|---|---|
| Human |
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Manufactured under ISO 14001:2015 quality management standards.
Manufactured under ISO 45001:2018 quality management standards.
Not intended for diagnostic or therapeutic use.
Substance does not appear on the SVHC candidate list.