Recombinant Human IL-36 Receptor Antagonist Protein/IL-36RN/IL-1F5
Recombinant Human IL-36 Receptor Antagonist Protein/IL-36RN/IL-1F5 supplied by Elabscience with collaborator-provided technical specifications. Read more ›
["Measured by its ability to inhibit IL-36 alpha, IL-36 beta or IL-36 gamma-induced IL-8 secretion in A431 human epithelial carcinoma cells. The ED50 for this effect is 23.14 ng/ml. ,17 kDa"]Product Description
IL-36RN is the stated recombinant protein target for this Elabscience product. The listing uses collaborator-supplied specifications to support research-use-only protein selection through ABMIUM.
Protein profile: reactive species/source: Human; expression system: E.coli; physical form: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.; tag: Human ,IL-36RN ,Recombinant Proteins; predicted molecular weight: 16.8 kDa.
Quality and formulation: purity: > 95 % as determined by reducing SDS-PAGE.; endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method..
Functional evidence: activity: Measured by its ability to inhibit IL-36 alpha, IL-36 beta or IL-36 gamma-induced IL-8 secretion in A431 human epithelial carcinoma cells. The ED<sub>50</sub> for this effect is 23.14 ng/ml.. In the ABMIUM matrix, collaborator-supplied functional evidence is marked C; unsupported application columns remain N.
Sequence coverage: 16.8 kDa.
Database references: UniProt: Q9UBH0 | NCBI Gene: 26525 | Gene symbol: IL-36RN.
Research Use Only.
Key Facts
| Target | IL-36RN |
| Also known as | FIL, UNQ, PRO, IL1F, IL1L, IL1HY, IL1RP, PSORS, IL36RN, FIL1, FIL1(DELTA), FIL1D, IL-36Ra, IL1F5, IL1HY1, IL1L1, IL1RP3, IL36RA, PSORP, PSORS14, UNQ1896, PRO4342, FIL1 Delta, IL-1 Delta, IL-1F5, IL-1HY1, IL-1L1, IL-1ra Homolog 1, IL-1-Related Protein 3, IL-1RP3, Interleukin-1 Delta, Interleukin-1 Family Member 5, Interleukin-1 HY1, Interleukin-1 Receptor Antagonist Homolog 1, Interleukin-1-Like Protein 1, Interleukin-36 Receptor Antagonist Protein |
| Species reactivity | Human |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Form / buffer | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Shelf life | 12 months |
| Research area | immunology |
| BIOACTIVITY | BINDING | CELL-BASED | IN VIVO | ELISA CAPTURE | |
|---|---|---|---|---|---|
| Human |
Specifications
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Manufactured under ISO 14001:2015 quality management standards.
Manufactured under ISO 45001:2018 quality management standards.
Not intended for diagnostic or therapeutic use.
Substance does not appear on the SVHC candidate list.