Recombinant Human CD122/IL-2RB Protein
Recombinant Human CD122/IL-2RB Protein supplied by Elabscience with collaborator-provided technical specifications. Read more ›
["1. Immobilized human IL2Rb at 10 μg/ml (100 μl/well) can bind biotinylated human IL2, The EC50 of biotinylated human IL2 is 0.1-0.24 μg/mL. 2. Measured by its ability to inhibit IL15-dependent proliferation of MO7e human megakaryocytic leukemic cells in the presence of 4.0 ng/mL of recombinant human IL-15.The ED50 for this effect is 1-4μg/mL. ,40 kDa"]Product Description
CD122/IL-2RB is the stated recombinant protein target for this Elabscience product. The listing uses collaborator-supplied specifications to support research-use-only protein selection through ABMIUM.
Protein profile: reactive species/source: Human; expression system: HEK293 Cells; physical form: Lyophilized from sterile 100mM NaCl, 50mM Tris, pH 7.5<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.; tag: Human ,CD122/IL-2RB ,Cytokines; predicted molecular weight: 25.2 kDa.
Quality and formulation: purity: > 90 % as determined by reducing SDS-PAGE.; endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method..
Functional evidence: activity: 1. Immobilized human IL2Rb at 10 μg/ml (100 μl/well) can bind biotinylated human IL2, The EC<sub>50</sub> of biotinylated human IL2 is 0.1-0.24 μg/mL. 2. Measured by its ability to inhibit IL15-dependent proliferation of MO7e human megakaryocytic leukemic cells in the presence of 4.0 ng/mL of recombinant human IL-15.The ED<sub>50</sub> for this effect is 1-4μg/mL.. In the ABMIUM matrix, collaborator-supplied functional evidence is marked C; unsupported application columns remain N.
Sequence coverage: 25.2 kDa.
Database references: UniProt: NP_000869.1 | NCBI Gene: 3560 | Gene symbol: CD122/IL-2RB.
Research Use Only.
Key Facts
| Target | CD122/IL-2RB |
| Also known as | P70, IL2RB, CD122, IL15RB, P70-75, IL-2Rβ, p75, IL-2RB, Interleukin-2 receptor subunit beta, IL-2 receptor subunit beta, IL-2R subunit beta, High affinity IL-2 receptor subunit beta, Interleukin-15 receptor subunit beta, p70-75 (p75), IL-2R&, beta, CD122 antigen, High affinity IL 2 receptor beta subunit, High affinity IL 2 receptor subunit beta, IL2 receptor, Interleukin 2 receptor beta, interleukin 2 receptor subunit beta, P70 75, P7075 |
| Species reactivity | Human |
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Form / buffer | Lyophilized from sterile 100mM NaCl, 50mM Tris, pH 7.5 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Shelf life | 12 months |
| Research area | Signal Transduction, immunology, Stem cells |
| BIOACTIVITY | BINDING | CELL-BASED | IN VIVO | ELISA CAPTURE | |
|---|---|---|---|---|---|
| Human |
Specifications
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Manufactured under ISO 14001:2015 quality management standards.
Manufactured under ISO 45001:2018 quality management standards.
Not intended for diagnostic or therapeutic use.
Substance does not appear on the SVHC candidate list.