CD122 Recombinant Protein from ProteoGenix; catalogue PX-P4103; research use only.
Know who made it. See the evidence. Buy through one marketplace.
The interleukin-2 receptor (IL-2R), also known as the β subunit receptor of the β subunit IL-2, subunit of the IL-2 β and IL-2RB receptor, participates in the immune response of T cells. ability to bind interleukin 2, CD122 / IL-2RB exists in three forms. The low affinity form is a monomer of the alpha subunit and does not participate in signal transmission. The intermediate affine form is composed of α / β subunit heterodimers, while the high affinity form is composed of α / β / gamma heterotrimers. Both forms of medium and high affinity for CD122 / IL-2RB are involved in receptor-mediated endocytosis and interleukin-2-mediated mitotic signal transduction. CD122 / IL-2RB expression is limited to older B22 + cells (CD43 + CD24- prepro B cells, fraction A), which can proliferate to IL-2 strongly without any stromal cells, but not to IL-15 A High affinity form of the receptor is expressed in activated T lymphocytes, activated B lymphocytes and activated macrophages. CD122 / IL-2RB plays a role in regulating normal lymphocyte development.
ProteoGenix catalogue number PX-P4103. For research use only.
Host: Mammalian cells; Expression system: Eukaryotic expression; Purity: >90% by SDS-PAGE; Molecular weight: 35-45kDa; Tag: C-terminal His Tag; Fragment: Met1-Asp239; Buffer: PBS pH7.5; Applications: ELISA, WB.
Available configurations: 50ug, 100ug, 1mg.
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
