Anti-ACSL4 Polyclonal Antibody from ProteoGenix; catalogue ARO-A22088; research use only.
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Anti-ACSL4 Polyclonal Antibody: A Powerful Tool for Studying Lipid Metabolism and Cancer Research
The Anti-ACSL4 Polyclonal Antibody is a highly specific and sensitive tool for studying lipid metabolism and cancer research. This antibody targets the ACSL4 protein, which plays a crucial role in the biosynthesis of fatty acids and their incorporation into cellular membranes. It is an essential enzyme for maintaining lipid homeostasis and has been implicated in various diseases, including cancer.
The ACSL4 protein belongs to the long-chain acyl-CoA synthetase (ACSL) family, which catalyzes the formation of fatty acyl-CoA from fatty acids and coenzyme A. The ACSL4 enzyme is primarily found in the endoplasmic reticulum (ER) and is responsible for activating long-chain fatty acids for various cellular processes, such as lipid synthesis, energy production, and membrane formation. It is also involved in the regulation of lipid droplet formation and lipid signaling pathways.
The Anti-ACSL4 Polyclonal Antibody is widely used in both basic and clinical research. It is a valuable tool for investigating the role of ACSL4 in lipid metabolism and its potential implications in various diseases, particularly cancer. This antibody has been extensively used in studies on breast cancer, prostate cancer, and melanoma, where ACSL4 overexpression has been observed. It has also been shown to play a role in drug resistance and metastasis, making it a potential therapeutic target for cancer treatment.
The Anti-ACSL4 Polyclonal Antibody has been used in a variety of experimental techniques, including Western blotting, immunohistochemistry, and immunofluorescence. It has been validated for use in human, mouse, and rat samples, ensuring its versatility for different research models. This antibody has been shown to have high specificity and sensitivity, allowing for accurate detection of ACSL4 expression levels in various tissues and cell lines.
In addition to cancer research, the Anti-ACSL4 Polyclonal Antibody has also been used in studies on lipid metabolism disorders, such as non-alcoholic fatty liver disease (NAFLD) and obesity. Its ability to specifically target ACSL4 makes it a valuable tool for understanding the role of this enzyme in these conditions and potentially identifying new therapeutic strategies.
In conclusion, the Anti-ACSL4 Polyclonal Antibody is a powerful and versatile tool for studying lipid metabolism and cancer research. Its high specificity and sensitivity, along with its various applications and experimental use cases, make it an essential addition to any laboratory studying these areas. With this antibody, researchers can gain a deeper understanding of the role of ACSL4 in disease and potentially identify new targets for treatment.
ProteoGenix catalogue number ARO-A22088. For research use only.
Target: Long-chain-fatty-acid--CoA ligase 4, EC:6.2.1.3, Arachidonate--CoA ligase, EC:6.2.1.15, Long-chain acyl-CoA synthetase 4, LACS 4, ACSL4, ACS4, FACL4, LACS4; Clonality: Polyclonal Antibody; Applications: IHC, ELISA.
Available configurations: 50ug, 100ug, 1mg.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Target | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP | ELISA | IHC |
|---|---|---|---|---|---|---|---|---|---|
| Long-chain-fatty-acid--CoA ligase 4, EC |
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
