Anticorps primaire fourni par Boster Bio
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Le Cluster de différenciation 86 (également connu sous le nom de CD86 et B7-2) est une protéine exprimée sur les cellules présentatrices d'antigène qui fournit les signaux costimulateurs nécessaires à l'activation et à la survie des lymphocytes T. Le gène CD86 code pour une protéine membranaire de type I qui est membre de la superfamille des immunoglobulines. Par cartographie par hybridation in situ fluorescente, le CD86, comme le CD80, a été cartographié sur le 3q21 humain. Les coactivateurs de présentation d'antigène B71 et B72, importants dans d'autres maladies thyroïdiennes à médiation immunitaire, sont importants pour l'infiltration lymphocytaire et la réponse immunitaire contre le carcinome thyroïdien.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IHC-P | IHC-F | IF/ICC | Cytométrie en flux | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Souris | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
CD86 identifies CD86 molecule in Homo sapiens (Human). This target record connects NCBI Gene 942, UniProtKB P42081 and related ABMIUM catalogue products.
Biological function: CD86 (B7-2) is an antigen-presenting-cell costimulatory molecule. It binds CD28 to support T-cell activation and also binds CTLA4, which negatively regulates T-cell activation and limits immune responses.
