ABMIUM target intelligence

CD86

CD86 molecule

CD86 identifies CD86 molecule in Homo sapiens (Human). This target record connects NCBI Gene 942, UniProtKB P42081 and related ABMIUM catalogue products.

Read full target overview
OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene942 UniProtP42081

ABMIUM research catalogue

Research Products

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Research context & evidence

About CD86

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

CD86 (B7-2) is an antigen-presenting-cell costimulatory molecule. It binds CD28 to support T-cell activation and also binds CTLA4, which negatively regulates T-cell activation and limits immune responses.

Experimental context

Research context

CD86 is widely studied in antigen-presenting cells, T-cell costimulation, immune checkpoints, adaptive immunity and inflammatory or tumour-immunology models. Reagent selection should consider species, activation state, sample type, assay format, application and supporting validation.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

T-lymphocyte activation antigen CD86B7-2B70BU63CD28LG2CD86 v6FUN-1LAB72B7CLS1Cd28l2ETC-1Ly-58MB7MB7-2TS/A-2